After AHAs and BHAs, a third family of acids is gaining ground: PHAs, or polyhydroxy acids. Their promise? Gentle skin renewal, even for reactive skin. Let's explore.
What are PHAs?
PHAs are renewal acids, cousins of AHAs (like glycolic or lactic acid). The most well-known are gluconolactone and lactobionic acid.
Their particularity lies in the size of their molecule, which is larger than that of classic AHAs: they therefore act more on the surface and more progressively. This explains their reputation for gentleness.
PHAs, or poly-hydroxy acids, form the third family of fruit acids after AHAs and BHAs. Their particularity is their size: their molecule is significantly larger, meaning it penetrates more slowly and less deeply.
This slowness is precisely what makes them suitable for sensitive skin. They detach dead cells and support cell renewal with a lower risk of irritation, at the cost of a more gradual action. They are also credited with antioxidant properties, which AHAs do not possess.
What PHAs bring to the skin
- Smoother skin texture and a fresher complexion, without abrupt changes.
- A hydrating effect: some PHAs also help the skin to retain water.
- Appreciated tolerance for skin that cannot tolerate more intense exfoliants.
Like all renewal active ingredients, PHAs act on the appearance and smoothness of the skin. They are cosmetic active ingredients, not treatments.
PHA or AHA: which to choose?
| AHA (glycolic, lactic) | PHA | |
|---|---|---|
| Molecule | Smaller | Larger |
| Action | More "penetrating" | More on the surface, gentler |
| Ideal for | Accustomed skin | Sensitive or beginner skin |
👉 To place PHAs in context, see our guide on Exfoliation and the Lactic Acid page.
For what skin type?
PHAs are often the first step towards chemical exfoliation for:
- sensitive or reactive skin,
- those who have poorly tolerated an AHA/BHA,
- those who want to revive radiance without risk of discomfort.
How to incorporate them
- In the evening, on clean skin, starting 2 times a week.
- Then hydrate to enhance comfort.
- SPF in the morning, as with all renewal acids.
A serum or cream formulated with PHAs should be used in the evening, two to three times a week to start. In a skincare routine already containing active ingredients, it's better to replace than to add: combining AHA, BHA, and PHA triples the strain on the skin.
For pigmented spots, the effect remains indirect and slow, as with any chemical exfoliation. In the anti-aging field, these ingredients improve skin texture regularity more than they act deeply—and that is already what is most quickly visible.
The Nopal Life Approach

Gentleness is not an option for us, it's a principle. PHAs perfectly embody this idea: renew without aggression. They naturally combine with soothing and nourishing treatments like prickly pear seed oil.
Frequently asked questions
Are PHAs really suitable for sensitive skin? That's precisely their strength: a more superficial and gradual action, often better tolerated.
Can they be used every day? Depending on tolerance, yes for some skin types — but always start progressively.
PHA and retinal together? Introduce them separately, then listen to your skin before combining them.
Is your skin sensitive? Find the right routine. 👉 Start my free diagnosis
Nopal Life — natural facial care with prickly pear. Information relating to skin appearance and comfort, not constituting medical advice. © Nopal Life.
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